European Porphyria NetworkLocal Anaesthesia (Including Dental) The safety of local anaesthetic agents remains a controversial issue due to experimental evidence that some of the local anaesthetic agents are porphyrogenic in either animal models (e.g. lidocaine) or cell culture (e.g. lidocaine, mepivicaine, prilocaine, bupivacaine). However despite this laboratory evidence, clinical experience has shown that most of these agents […]
Inhalt 1. Was ist eine Porphyria cutanea tarda (PCT)? 2. Wodurch entsteht eine Porphyria cutanea tarda? 3. Ist die Porphyria cutanea tarda angeboren? 4. Was sind die wichtigsten prädisponierenden Faktoren? 5. Welche Symptome entstehen bei PCT? 6. Wie wird die PCT diagnostiziert? 7. Kann eine PCT geheilt werden? 8. Wie kann die PCT behandelt […]
It has been decided to set up a network of specialist porphyria laboratories in which there will be collaboration and a quality assurance scheme. All laboratories listed on this website should fulfill the following criteria: Able to distinguish, using biochemical testing, between all types of porphyria Able to offer specialist detailed interpretation of results with […]
Background information This information applies only to treatment of patients with an acute porphyria (AIP, HCP, VP). Evidence on safety of drugs is drawn from three main sources: Clinical reports Experimental systems ( e.g. chick embryo hepatocyte culture) Drug metabolism data Combinations of drugs plus other factors (stress, infection, malnutrition) may increase the risk of […]
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Contents 1. What is Erythropoietic Protoporphyria ? 2. What causes EPP ? 3. How is EPP inherited? 4. Will my children inherit EPP? 5. What are the symptoms of EPP? 6. What does EPP look like? 7. How is EPP diagnosed? 8. Is there a cure for EPP? 9. How can EPP be treated? […]
Porphyria Cutanea Tarda (PCT) Contents 1. What is Porphyria Cutanea Tarda (PCT)? 2. What causes PCT? 3. Is PCT inherited? 4. What are the most important predisposing factors? 5. What are the symptoms of PCT? 6. How is PCT diagnosed? 7. Can PCT be cured? 8. How can PCT be treated? 9. What can I […]
Spis treści 1. Co to są porfirie i jak je różnicujemy? 2. Dlaczego choroby te nazywamy porfiriami? 3. Dlaczego porfiryny są ważne? 4. Dlaczego porfiryny i ich prekursory powodują chorobę? PODZIĘKOWANIA Informacje te są przewidziane dla pacjentów i ich rodzin z różnymi typami porfirii. Zostały napisane i sprawdzone przez specjalistów z dziedziny porfirii i […]
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How to use the information ? This website contains : A list of drugs that are considered SAFE A list of drugs which are considered UNSAFE Guidance on common prescribing problems A link to a searchable drug list In most circumstances the SAFE and UNSAFE drug lists may be used to choose an appropriate drug. […]